Cerene® Endometrial Cryotherapy
Designed to significantly reduce heavy period bleeding and cramping. No incisions or anesthesia needed—done right in your doctor’s office.
Say Hello to Cerene
Cerene is an endometrial cryotherapy that uses cooling technology to remove the lining of the uterus (endometrium), which is often the cause of heavy bleeding and discomfort.
Period Relief
Significantly reduces heavy bleeding and painful periods with most women returning to daily activities within 24 hours
Convenient
Treatment
A treatment that can be performed comfortably in your doctor’s office without anesthesia or incisions
High
Satisfaction
9 out of 10 women had little to no limitations in their activities after Cerene†
Real Patient Results
were satisfied
with Cerene†
would recommend Cerene to family and friends††
had normal, light, or no periods after Cerene†
had a reduction in cramping†††
† Patient-reported data are 1 year after treatment with durable results at 3 years
†† Patient-reported data include definitely and consider recommending Cerene and are 1 year after treatment with durable results at 3 years
††† Improvement reported one year after treatment for patients reporting severe/very severe cramping
How it Works
Step 1: The Cerene Device is gently inserted into the uterus, and safety checks are completed
Step 2: Cryotherapy is delivered for 2 1/2 minutes to treat the endometrium, while providing a natural, pain-relieving effect
Step 3: At the end of the treatment, the Cerene Device is carefully removed
"Life for me has changed quite a bit since having the Cerene treatment. I no longer have to plan my daily activities around my periods."
— Rachel, Cerene Patient
Frequently Asked Questions
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Cerene is a safe and effective treatment to reduce heavy menstrual bleeding. The treatment uses cooling technology to remove the uterine lining (endometrium) in premenopausal women. As monthly shedding of the endometrium causes menstrual blood flow, removing the lining of the uterine cavity can result in reduced or no menstrual bleeding.
Cerene does not require sedation or general anesthesia, and it can be performed in the comfort and familiarity of your gynecologist’s office.
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Cerene is for premenopausal women who have heavy periods due to benign causes that interfere with the quality of their daily lives. Cerene is also only for women who no longer want to have children. Please consult with your doctor to see if Cerene is right for you.
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Heavy menstrual bleeding is a common problem that affects about 1 in 5 women.1 It’s most likely to start between the ages of 30 and 40, but some women experience heavy menstrual bleeding from an earlier age. If you soak your sanitary protection (pads or tampons) more than once an hour, your bleeding may be excessive. You may also feel weak, tired, and have no energy, making it difficult to work, exercise, and be socially and sexually active.
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Cerene is performed in the comfort of your doctor’s office and most patients report returning to their activities within 24 hours after the treatment. The actual treatment time is only 2.5 minutes (as part of a 7-minute total time including insertion, safety checks, and removal).
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Cerene is FDA approved. It was studied in a FDA pivotal clinical study that showed it is safe and effective in treating heavy periods due to benign causes in premenopausal women for whom childbearing is complete. No serious device-related adverse events were reported.
Please refer to the Patient Labeling for complete information on Cerene, including risks and benefits and to understand if Cerene is right for you. Patient Labeling